Gluconeogenesis

CONTENTS What is gluconeogenesis? Why is gluconeogenesis important? Where does gluconeogenesis occur? Irreversible steps of gluconeogenesis From pyruvate to phosphoenolpyruvate Phosphoenolpyruvate precursor: pyruvate or alanine Phosphoenolpyruvate precursor: lactate From fructose 1,6-bisphosphate to fructose 6-phosphate From glucose 6-phosphate to glucose Gluconeogenesis: energetically expensive Coordinated regulation of gluconeogenesis and glycolysis Regulation of gluconeogenesis Pyruvate carboxylase Fructose 1,6-bisphosphatase […]

Cori cycle: definition, function, biochemistry, involved tissues

CONTENTS What is the Cori cycle? Where does the Cori cycle occur? The steps of the Cori cycle Lactate dehydrogenase Other metabolic fates of lactate Energy cost of the glucose-lactate cycle Is the Cori cycle a futile cycle? The Cori cycle and glucose-alanine cycle References What is the Cori cycle? The Cori cycle, or glucose-lactate […]

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